STAVUDINE is an antiretroviral drug. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. It will not stop the spread of HIV to others.

They need to know if you have any of these conditions:

• diabetes
• drink alcohol daily
• gallstones
• kidney disease
• liver disease
• history of pancreatitis
• tingling, numbness in the hands, feet
• an unusual or allergic reaction to stavudine, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

Take this medicine by mouth with a glass of water. You may take this medicine with or without food. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as newborns for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Do not take this medicine with any of the following medications:

• zalcitabine, ddC
• zidovudine, AZT

This medicine may also interact with the following medications:

• didanosine, ddI
• doxorubicin
• hydroxyurea
• interferon
• ribavirin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.

HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.

Do not treat severe stomach pain, nausea or vomiting with over-the-counter medicines. Contact your doctor.

This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.

Side effects that you should report to your doctor or health care professional as soon as possible:

• breathing problems
• increased hunger or thirst
• increased urination
• muscle weakness in arms and legs
• nausea, vomiting, unusual stomach upset or pain
• tingling, pain, burning, or numbness in the hands or feet
• unusual bleeding or bruising
• unusually weak or tired
• weight gain around waist, back, or thinning of face, arms, legs

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• diarrhea
• difficulty sleeping
• fever, chills
• headache
• loss of appetite
• muscle pain
• weight loss

This list may not describe all possible side effects.

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.