NEBIVOLOL is a beta-blocker. Beta-blockers reduce the workload on the heart and help it to beat more regularly. This medicine is used to treat high blood pressure.

They need to know if you have any of these conditions:

• diabetes
• heart or vessel disease like slow heartrate, worsening heart failure, heart block, sick sinus syndrome or Raynaud's disease
• kidney disease
• liver disease
• lung disease like asthma or emphysema
• pheochromocytoma
• thyroid disease
• an unusual or allergic reaction to nebivolol, other beta-blockers, medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

Take this medicine by mouth with a glass of water. You can take this medicine with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine suddenly. This could lead to serious heart-related effects.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Do not take this medicine with the following:

• sotalol

This medicine may also interact with the following:

• cimetidine
• clonidine
• diltiazem
• digoxin
• fluoxetine
• guanethidine
• medicines called beta blockers used for blood pressure
• paroxetine
• propafenone
• quinidine
• reserpine
• sildenafil
• verapamil

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Visit your doctor or health care professional for regular checks on your progress. Check your heart rate and blood pressure regularly while you are taking this medicine. Ask your doctor or health care professional what your heart rate and blood pressure should be, and when you should contact him or her.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.

This medicine can affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.

Do not treat yourself for coughs, colds, or pain while you are taking this medicine without asking your doctor or health care professional for advice. Some ingredients may increase your blood pressure.

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• breathing problems
• chest pain
• cold, tingling, or numb hands or feet
• dark urine
• general ill feeling or flu-like symptoms
• irregular heartbeat
• light-colored stools
• loss of appetite, nausea
• right upper belly pain
• slow heart rate
• swollen legs or ankles
• unusual bleeding or bruising
• unusually weak or tired
• vomiting
• yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• diarrhea
• dizziness
• dry or burning eyes
• headache
• nausea
• tiredness
• trouble sleeping

This list may not describe all possible side effects.

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.