MISOPROSTOL helps to prevent stomach ulcers in patients using nonsteroidal antiinflammatory drugs (NSAIDS, drugs commonly used for arthritis, inflammation, and pain). Misoprostol reduces the amount of acid produced in the stomach and protects the stomach lining from the effects of acid.

They need to know if you have any of these conditions:

• Crohn's disease
• heart disease
• kidney disease
• ulcerative colitis
• an unusual or allergic reaction to misoprostol, prostaglandins, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

Take this medicine by mouth with a full glass of water. Take this medicine with food.Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

• antacids

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

Do not smoke cigarettes or drink alcohol. These increase irritation to your stomach and can make it more susceptible to damage from medicine like ibuprofen and aspirin.

If you are female, do not use this medicine if you are pregnant. Do not get pregnant while taking this medicine and for at least one month (one full menstrual cycle) after stopping this medicine. If you can become pregnant, use a reliable form of birth control while taking this medicine. Talk to your doctor about birth control options. If you do become pregnant, think you are pregnant, or want to become pregnant, immediately call your doctor for advice.

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• chest pain
• fainting spells
• severe diarrhea
• sudden shortness of breath
• unusual vaginal bleeding, pelvic pain or cramping

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• dizziness
• headache
• menstrual irregularity, spotting or cramps
• mild diarrhea
• nausea
• stomach upset or cramps

This list may not describe all possible side effects.

Keep out of the reach of children.

Store at room temperature below 25 degrees C (77 degrees F). Keep in a dry place. Protect from moisture. Throw away any unused medicine after the expiration date.