PERINDOPRIL is an ACE inhibitor. This medicine is used to treat high blood pressure. This medicine is also used in patients with coronary artery disease. It may reduce the risk of heart attack in these patients.

They need to know if you have any of these conditions:

• bone marrow disease
• heart or blood vessel disease
• if you are on a special diet, such as a low-salt diet
• immune system disease like lupus
• kidney or liver disease
• low blood pressure
• previous swelling of the tongue, face, or lips with difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat
• an unusual or allergic reaction to perindopril, other ACE inhibitors, insect venom, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

Take this medicine by mouth with a glass of water. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine except on the advice of your doctor or health care professional.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

• diuretics
• gentamicin
• lithium
• medicines for high blood pressure
• NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
• potassium salts or potassium supplements

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor or health care professional what your blood pressure should be and when you should contact him or her. Call your doctor or health care professional if you notice an irregular or fast heart beat.

Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.

Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.

Avoid salt substitutes unless you are told otherwise by your doctor or health care professional.

Do not treat yourself for coughs, colds, or pain while you are taking this medicine without asking your doctor or health care professional for advice. Some ingredients may increase your blood pressure

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash or hives, swelling of the hands, feet, face, lips, throat, or tongue
• chest pain
• decreased amount of urine passed
• difficulty breathing, or difficulty swallowing
• dizziness, light headedness or fainting spells
• fever or chills
• numbness or tingling in your fingers or toes
• nausea and vomiting
• stomach or abdominal pain
• swelling of your legs or ankles

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• cough
• decreased sexual function or desire
• diarrhea
• headache

This list may not describe all possible side effects.

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date